Iron availability and oxygen tension regulate the Yersinia Ysc type III secretion system to enable disseminated infection.

Iron availability and oxygen tension regulate the Yersinia Ysc type III secretion system to enable disseminated infection.

The enteropathogen Yersinia pseudotuberculosis and the related plague agent Y. pestis require the Ysc type III secretion system (T3SS) to subvert phagocyte defense mechanisms and cause disease. Yet type III secretion (T3S) in Yersinia induces growth arrest and innate immune recognition, necessitatin...

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Bibliographic Details
Main Authors: Diana Hooker-Romero, Erin Mettert, Leah Schwiesow, David Balderas, Pablo A Alvarez, Anadin Kicin, Azuah L Gonzalez, Gregory V Plano, Patricia J Kiley, Victoria Auerbuch
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-12-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1008001

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https://doi.org/10.1371/journal.ppat.1008001

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