Evaluation of Cysteinyl Leukotriene Signaling as a Therapeutic Target for Colorectal Cancer

Colorectal cancer is the third most common cancer worldwide and is associated with significant morbidity and mortality. Current pharmacotherapy options include cytotoxic chemotherapy, anti-VEGF and anti-EGFR targeting drugs, but these are limited by toxic side effects, limited responses and ultimate...

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Bibliographic Details
Main Authors: Lorraine Burke, Clare T. Butler, Adrian Murphy, Bruce Moran, William M Gallagher, Jacintha O'Sullivan, Breandán N. Kennedy
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-09-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fcell.2016.00103/full