Is a composite reference standard (CRS) an alternative to culture in assessment and validation of a single tube nested in-house PCR for TB diagnosis?

Introduction: Delay in diagnosis of paucibacillary extra pulmonary tuberculosis (TB) and of smear negative TB has hampered the efforts taken by Control Programs to curb its spread. Better efforts to control spread of TB require more accurate and rapid diagnostic test. Aims: To facilitate early diagn...

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Bibliographic Details
Main Authors: Minal Deshmukh, Chaitali Nikam, Trupti Ragte, Anjali Shetty, Camilla Rodrigues
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2013-10-01
Series:Egyptian Journal of Chest Disease and Tuberculosis
Subjects:
CRS
Online Access:http://www.sciencedirect.com/science/article/pii/S0422763813002069