BaiCD gene cluster abundance is negatively correlated with Clostridium difficile infection.

Clostridium difficile infection (CDI) is a major cause of hospital-acquired diarrhea. Secondary bile acids were shown to confer resistance to colonization by C. difficile. 7α-dehydroxylation is a key step in transformation of primary to secondary bile acids and required genes have been located in a...

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Main Authors: Philipp Solbach, Patrick Chhatwal, Sabrina Woltemate, Evelina Tacconelli, Michael Buhl, Markus Gerhard, Christoph K Thoeringer, Maria J G T Vehreschild, Nathalie Jazmati, Jan Rupp, Michael P Manns, Oliver Bachmann, Sebastian Suerbaum
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5940204?pdf=render