BaiCD gene cluster abundance is negatively correlated with Clostridium difficile infection.
Clostridium difficile infection (CDI) is a major cause of hospital-acquired diarrhea. Secondary bile acids were shown to confer resistance to colonization by C. difficile. 7α-dehydroxylation is a key step in transformation of primary to secondary bile acids and required genes have been located in a...
Main Authors: | Philipp Solbach, Patrick Chhatwal, Sabrina Woltemate, Evelina Tacconelli, Michael Buhl, Markus Gerhard, Christoph K Thoeringer, Maria J G T Vehreschild, Nathalie Jazmati, Jan Rupp, Michael P Manns, Oliver Bachmann, Sebastian Suerbaum |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2018-01-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC5940204?pdf=render |
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