Eriodictyol Attenuates Myocardial Ischemia-Reperfusion Injury through the Activation of JAK2

Eriodictyol Attenuates Myocardial Ischemia-Reperfusion Injury through the Activation of JAK2

Myocardial ischemia-reperfusion (I/R) injury remains the leading risk factor of disability and mortality worldwide. In this study, the myocardial protective effect of eriodictyol (EDT) and the underlying mechanism in an ex vivo model of global myocardial I/R was investigated. After treatment with di...

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Bibliographic Details
Main Authors: Defang Li, Ning Lu, Jichun Han, Xiaoyu Chen, Wenjin Hao, Wenjuan Xu, Xiaona Liu, Lei Ye, Qiusheng Zheng
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-01-01
Series:Frontiers in Pharmacology
Subjects:
eriodictyol
myocardial ischemia-reperfusion
apoptosis
inflammation
JAK2
Online Access:http://journal.frontiersin.org/article/10.3389/fphar.2018.00033/full

Internet

http://journal.frontiersin.org/article/10.3389/fphar.2018.00033/full

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