Polysaccharides From Lentinus Edodes Inhibits Lymphangiogenesis via the Toll-Like Receptor 4/JNK Pathway of Cancer-Associated Fibroblasts

Polysaccharides From Lentinus Edodes Inhibits Lymphangiogenesis via the Toll-Like Receptor 4/JNK Pathway of Cancer-Associated Fibroblasts

Polysaccharides from Lentinus edodes (L. edodes) have been successfully used as adjuvant chemotherapy drug to treat lymphatic metastasis in some malignancies, such as colorectal cancer (CRC), lung cancer and gastric cancer. The CRC could metastasize via lymphatic vessels. Lymphatic metastasis is com...

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Bibliographic Details
Main Authors: Yuanyuan Wang, Yanqiong Zeng, Linyu Zhu, Jiajia Wan, Ningjing Lei, Xiaohan Yao, Xixi Duan, Yana Zhang, Yanru Cheng, Ning Tao, Zhihai Qin
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-02-01
Series:Frontiers in Oncology
Subjects:
colorectal cancer
lymphangiogenesis
cancer-associated fibroblasts
VEGF-C
Lentinus edodes polysaccharides (MPSSS)
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2020.547683/full

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https://www.frontiersin.org/articles/10.3389/fonc.2020.547683/full

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