A Suitable Functionalization of Nitroindazoles with Triazolyl and Pyrazolyl Moieties via Cycloaddition Reactions

A Suitable Functionalization of Nitroindazoles with Triazolyl and Pyrazolyl Moieties via Cycloaddition Reactions

The alkylation of a series of nitroindazole derivatives with 1,2-dibromoethane afforded the corresponding <i>N</i>-(2-bromoethyl)- and <i>N</i>-vinyl-nitro-1<i>H</i>-indazoles. The Cu(I)-catalysed azide- alkyne 1,3-dipolar cycloaddition was selected to substitute...

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Bibliographic Details
Main Authors: Mohammed Eddahmi, Nuno M. M. Moura, Latifa Bouissane, Ouafa Amiri, M. Amparo F. Faustino, José A. S. Cavaleiro, Ricardo F. Mendes, Filipe A. A. Paz, Maria G. P. M. S. Neves, El Mostapha Rakib
Format: Article
Language:English
Published: MDPI AG 2019-12-01
Series:Molecules
Subjects:
nitrogen heterocycles
nitroindazole
alkylation
click chemistry
1,3-dipolar cycloaddition
nitrile imines
Online Access:https://www.mdpi.com/1420-3049/25/1/126

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https://www.mdpi.com/1420-3049/25/1/126

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