Deficiency of MIF Accentuates Overloaded Compression-Induced Nucleus Pulposus Cell Oxidative Damage via Depressing Mitophagy

Established studies proved that mechanical compression loading had multiple effects on the biological behavior of the intervertebral disc (IVD). However, the regulating mechanism involved in this process remains unclear. The current study is aimed at exploring the potential bioregulators and signali...

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Bibliographic Details
Main Authors: Yiyang Wang, Yanzhu Hu, Haoming Wang, Ningyuan Liu, Lei Luo, Chen Zhao, Dandan Zhou, Hang Tong, Pei Li, Qiang Zhou
Format: Article
Language:English
Published: Hindawi Limited 2021-01-01
Series:Oxidative Medicine and Cellular Longevity
Online Access:http://dx.doi.org/10.1155/2021/6192498