Knockdown of HE4 suppresses aggressive cell growth and malignant progression of ovarian cancer by inhibiting the JAK/STAT3 pathway

Human epididymis protein 4 (HE4) is well known to be a predictor of ovarian cancer clinically. HE4 is reported to play crucial roles in ovarian cancer progression and metastasis. The purpose of the present study was to explore its biological role and molecular mechanism in ovarian cancer. In our stu...

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Bibliographic Details
Main Authors: Aihong Wang, Canhui Jin, Xiaoyu Tian, Ying Wang, Hongyu Li
Format: Article
Language:English
Published: The Company of Biologists 2019-09-01
Series:Biology Open
Subjects:
HE4
Online Access:http://bio.biologists.org/content/8/9/bio043570