Palmitate activates autophagy in INS-1E β-cells and in isolated rat and human pancreatic islets.

Palmitate activates autophagy in INS-1E β-cells and in isolated rat and human pancreatic islets.

We have investigated the in vitro effects of increased levels of glucose and free fatty acids on autophagy activation in pancreatic beta cells. INS-1E cells and isolated rat and human pancreatic islets were incubated for various times (from 2 to 24 h) at different concentrations of glucose and/or pa...

Full description

Bibliographic Details
Main Authors: Luisa Martino, Matilde Masini, Michela Novelli, Pascale Beffy, Marco Bugliani, Lorella Marselli, Pellegrino Masiello, Piero Marchetti, Vincenzo De Tata
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22563482/?tool=EBI

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22563482/?tool=EBI

Similar Items