A novel highly reproducible and lethal nonhuman primate model for orthopox virus infection.

The intentional re-introduction of Variola virus (VARV), the agent of smallpox, into the human population is of great concern due its bio-terroristic potential. Moreover, zoonotic infections with Cowpox (CPXV) and Monkeypox virus (MPXV) cause severe diseases in humans. Smallpox vaccines presently av...

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Bibliographic Details
Main Authors: Marit Kramski, Kerstin Mätz-Rensing, Christiane Stahl-Hennig, Franz-Josef Kaup, Andreas Nitsche, Georg Pauli, Heinz Ellerbrok
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2861679?pdf=render