Targeting Cholesterol Metabolism as Efficient Antiviral Strategy Against the Hepatitis E VirusSummary

Background and aims: The Hepatitis E virus hijacks the endosomal system for its release. These structures are highly dependent on cholesterol. Hence, this study investigates the impact of HEV on cholesterol-metabolism, the effect of intracellular cholesterol content on HEV-release and the potential...

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Bibliographic Details
Main Authors: Mirco Glitscher, David Heiler Martín, Kathrin Woytinek, Benjamin Schmidt, Denna Tabari, Catharina Scholl, Julia C. Stingl, Evelyn Seelow, Mira Choi, Eberhard Hildt
Format: Article
Language:English
Published: Elsevier 2021-01-01
Series:Cellular and Molecular Gastroenterology and Hepatology
Subjects:
HEV
Online Access:http://www.sciencedirect.com/science/article/pii/S2352345X21000357