Treatment With Suboptimal Dose of Benznidazole Mitigates Immune Response Molecular Pathways in Mice With Chronic Chagas Cardiomyopathy

Treatment With Suboptimal Dose of Benznidazole Mitigates Immune Response Molecular Pathways in Mice With Chronic Chagas Cardiomyopathy

Chronic Chagas cardiomyopathy (CCC) is the most frequent and severe form of Chagas disease, a neglected tropical illness caused by the protozoan Trypanosoma cruzi, and the main cause of morbimortality from cardiovascular problems in endemic areas. Although efforts have been made to understand the si...

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Bibliographic Details
Main Authors: Priscila Silva Grijó Farani, Khodeza Begum, Glaucia Vilar-Pereira, Isabela Resende Pereira, Igor C. Almeida, Sourav Roy, Joseli Lannes-Vieira, Otacilio Cruz Moreira
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-07-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
Chagas disease
Trypanosoma cruzi
cardiomyopathy
immune response
TaqMan array
benznidazole
Online Access:https://www.frontiersin.org/articles/10.3389/fcimb.2021.692655/full

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https://www.frontiersin.org/articles/10.3389/fcimb.2021.692655/full

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