In vitro and in vivo growth inhibitory activities of cryptolepine hydrate against several Babesia species and Theileria equi.

Piroplasmosis treatment has been based on the use of imidocarb dipropionate or diminazene aceturate (DA), however, their toxic effects. Therefore, the discovery of new drug molecules and targets is urgently needed. Cryptolepine (CRY) is a pharmacologically active plant alkaloid; it has significant p...

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Bibliographic Details
Main Authors: Gaber El-Saber Batiha, Amany Magdy Beshbishy, Luay M Alkazmi, Eman H Nadwa, Eman K Rashwan, Naoaki Yokoyama, Ikuo Igarashi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-08-01
Series:PLoS Neglected Tropical Diseases
Online Access:https://doi.org/10.1371/journal.pntd.0008489