Chemoprevention of DMH-Induced Early Colon Carcinogenesis in Male BALB/c Mice by Administration of <i>Lactobacillus Paracasei</i> DTA81

Chemoprevention of DMH-Induced Early Colon Carcinogenesis in Male BALB/c Mice by Administration of <i>Lactobacillus Paracasei</i> DTA81

We evaluated the effects of the probiotic candidate <i>Lactobacillus paracasei</i> DTA81 (DTA81) on liver oxidative stress, colonic cytokine profile, and gut microbiota in mice with induced early colon carcinogenesis (CRC) by 1,2-dimethylhydrazine (DMH). Animals were divided into four di...

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Bibliographic Details
Main Authors: Vinícius da Silva Duarte, Bruna Cristina dos Santos Cruz, Armin Tarrah, Roberto Sousa Dias, Luiza de Paula Dias Moreira, Wilson José Fernandes Lemos Junior, Lívia Carneiro Fidélis Silva, Gabriele Rocha Santana, Leandro Licursi de Oliveira, Maria do Carmo Gouveia Peluzio, Hilario Cuquetto Mantovani, Viviana Corich, Alessio Giacomini, Sérgio Oliveira de Paula
Format: Article
Language:English
Published: MDPI AG 2020-12-01
Series:Microorganisms
Subjects:
probiotic
colorectal cancer
<i>Lactobacillus paracasei</i> DTA81
1,2-dimethylhydrazine (DMH)
short-chain fatty acids
16S rRNA
Online Access:https://www.mdpi.com/2076-2607/8/12/1994

Internet

https://www.mdpi.com/2076-2607/8/12/1994

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