Edge-localized alteration in pluripotency state of mouse ES cells forming topography-confined layers on designed mesh substrates

Self-organization of pluripotent stem cells during tissue formation is directed by the adhesion microenvironment, which defines the resulting tissue topography. Although the influence of tissue topography on pluripotency state has been inferred, this aspect of self-organization remains largely unexp...

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Bibliographic Details
Main Authors: Yuta Ando, Kennedy Omondi Okeyo, Junko Sunaga, Taiji Adachi
Format: Article
Language:English
Published: Elsevier 2021-05-01
Series:Stem Cell Research
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1873506121001987