Acrylamide Analog as a Novel Nitric Oxide-Independent Soluble Guanylyl Cyclase Activator
Soluble guanylyl cyclase (sGC) is a target enzyme for endogenous nitric oxide (NO), and it converts GTP to cyclic GMP (guanosine 3’,5’-cyclic monophosphate) as part of a cascade that results in physiological processes such as smooth muscle relaxation, neurotransmission, and inhibition of platelet ag...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2006-01-01
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Series: | Journal of Pharmacological Sciences |
Online Access: | http://www.sciencedirect.com/science/article/pii/S1347861319343981 |