Impact of Cyanidin-3-Glucoside on Glycated LDL-Induced NADPH Oxidase Activation, Mitochondrial Dysfunction and Cell Viability in Cultured Vascular Endothelial Cells

Impact of Cyanidin-3-Glucoside on Glycated LDL-Induced NADPH Oxidase Activation, Mitochondrial Dysfunction and Cell Viability in Cultured Vascular Endothelial Cells

Elevated levels of glycated low density lipoprotein (glyLDL) are frequently detected in diabetic patients. Previous studies demonstrated that glyLDL increased the production of reactive oxygen species (ROS), activated NADPH oxidase (NOX) and suppressed mitochondrial electron transport chain (mETC) e...

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Bibliographic Details
Main Authors: Xueping Xie, Ruozhi Zhao, Garry X. Shen
Format: Article
Language:English
Published: MDPI AG 2012-11-01
Series:International Journal of Molecular Sciences
Subjects:
cyanidin-3-glucoside
glycated LDL
NADPH oxidase
endothelial cells
mitochondrial electron transport chain enzymes
cell viability
Online Access:http://www.mdpi.com/1422-0067/13/12/15867

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http://www.mdpi.com/1422-0067/13/12/15867

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