Proteolytic cleavage of amyloid precursor protein by ADAM10 mediates proliferation and migration in breast cancerResearch in context section

Background: Amyloid precursor protein (APP), best known for its association with Alzheimer disease, has recently been implicated in breast cancer progression. However, the precise mechanism involved remains unclear. Here, we investigated the role of APP proteolytic cleavage in breast cancer function...

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Bibliographic Details
Main Authors: Julia Y.S. Tsang, Michelle A. Lee, Tsz-Hei Chan, Joshua Li, Yun-Bi Ni, Yan Shao, Siu-Ki Chan, Sai-Yin Cheungc, Kwok-Fai Lau, Gary M.K. Tse
Format: Article
Language:English
Published: Elsevier 2018-12-01
Series:EBioMedicine
Online Access:http://www.sciencedirect.com/science/article/pii/S235239641830505X