Sampling strategies to evaluate the prognostic value of a new biomarker on a time-to-event end-point
Abstract Background The availability of large epidemiological or clinical data storing biological samples allow to study the prognostic value of novel biomarkers, but efficient designs are needed to select a subsample on which to measure them, for parsimony and economical reasons. Two-phase stratifi...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2021-04-01
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Series: | BMC Medical Research Methodology |
Subjects: | |
Online Access: | https://doi.org/10.1186/s12874-021-01283-0 |