dsRNA-Dependent Protein Kinase PKR and its Role in Stress, Signaling and HCV Infection

The double-stranded RNA-dependent protein kinase PKR plays multiple roles in cells, in response to different stress situations. As a member of the interferon (IFN)‑Stimulated Genes, PKR was initially recognized as an actor in the antiviral action of IFN, due to its ability to control translation, th...

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Bibliographic Details
Main Authors: Eliane F. Meurs, Stéphanie Dabo
Format: Article
Language:English
Published: MDPI AG 2012-10-01
Series:Viruses
Subjects:
PKR
IFN
PRR
HCV
Online Access:http://www.mdpi.com/1999-4915/4/11/2598