Evidence that a RecQ helicase slows senescence by resolving recombining telomeres.
RecQ helicases, including Saccharomyces cerevisiae Sgs1p and the human Werner syndrome protein, are important for telomere maintenance in cells lacking telomerase activity. How maintenance is accomplished is only partly understood, although there is evidence that RecQ helicases function in telomere...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2007-06-01
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| Series: | PLoS Biology |
| Online Access: | http://europepmc.org/articles/PMC1885831?pdf=render |