Anti-Inflammatory, Anti-Diabetic, and Anti-Alzheimer’s Effects of Prenylated Flavonoids from Okinawa Propolis: An Investigation by Experimental and Computational Studies

Anti-Inflammatory, Anti-Diabetic, and Anti-Alzheimer’s Effects of Prenylated Flavonoids from Okinawa Propolis: An Investigation by Experimental and Computational Studies

Okinawa propolis (OP) and its major ingredients were reported to have anti-cancer effects and lifespan-extending effects on Caenorhabditis elegans through inactivation of the oncogenic kinase, p21-activated kinase 1 (PAK1). Herein, five prenylated flavonoids from OP, nymphaeol-A (NA), nymphaeol-B (N...

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Bibliographic Details
Main Authors: Md Shahinozzaman, Nozomi Taira, Takahiro Ishii, Mohammad A. Halim, Md Amzad Hossain, Shinkichi Tawata
Format: Article
Language:English
Published: MDPI AG 2018-09-01
Series:Molecules
Subjects:
Okinawa propolis
prenylated flavonoids
inflammation
α-glucosidase
acetylcholinesterase
molecular docking
density functional theory
p21-activated kinase 1
Online Access:http://www.mdpi.com/1420-3049/23/10/2479

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http://www.mdpi.com/1420-3049/23/10/2479

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