Id2 deletion attenuates Apc-deficient ileal tumor formation

The expression level of inhibitor of DNA binding 2 (Id2) is increased in colorectal carcinomas and is positively correlated with poor prognosis. However, the functional significance of Id2 in intestinal tumorigenesis has not been fully defined using genetic approaches. Here, we show that Id2 promote...

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Bibliographic Details
Main Authors: Kyoko Biyajima, Fumihiko Kakizaki, Xiaodong Shen, Kentaro Mori, Manabu Sugai, M. Mark Taketo, Yoshifumi Yokota
Format: Article
Language:English
Published: The Company of Biologists 2015-08-01
Series:Biology Open
Subjects:
Apc
Id2
Online Access:http://bio.biologists.org/content/4/8/993