Blockade of the SNARE protein syntaxin 1 inhibits glioblastoma tumor growth.

Glioblastoma (GBM) is the most prevalent adult brain tumor, with virtually no cure, and with a median overall survival of 15 months from diagnosis despite of the treatment. SNARE proteins mediate membrane fusion events in cells and are essential for many cellular processes including exocytosis and n...

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Main Authors: Fausto Ulloa, Alba Gonzàlez-Juncà, Delphine Meffre, Pablo José Barrecheguren, Ramón Martínez-Mármol, Irene Pazos, Núria Olivé, Tiziana Cotrufo, Joan Seoane, Eduardo Soriano
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4372377?pdf=render