DNA Barcoding in Nonhuman Primates Reveals Important Limitations in Retrovirus Integration Site Analysis

DNA Barcoding in Nonhuman Primates Reveals Important Limitations in Retrovirus Integration Site Analysis

In vivo tracking of retrovirus-tagged blood stem and progenitor cells is used to study hematopoiesis. Two techniques are used most frequently: sequencing the locus of retrovirus insertion, termed integration site analysis, or retrovirus DNA barcode sequencing. Of these, integration site analysis is...

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Bibliographic Details
Main Authors: Jennifer E. Adair, Mark R. Enstrom, Kevin G. Haworth, Lauren E. Schefter, Reza Shahbazi, Daniel R. Humphrys, Shaina Porter, Kenric Tam, Matthew H. Porteus, Hans-Peter Kiem
Format: Article
Language:English
Published: Elsevier 2020-06-01
Series:Molecular Therapy: Methods & Clinical Development
Online Access:http://www.sciencedirect.com/science/article/pii/S2329050120300516

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http://www.sciencedirect.com/science/article/pii/S2329050120300516

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