In Silico Oncology: Quantification of the In Vivo Antitumor Efficacy of Cisplatin-Based Doublet Therapy in Non-Small Cell Lung Cancer (NSCLC) through a Multiscale Mechanistic Model.

In Silico Oncology: Quantification of the In Vivo Antitumor Efficacy of Cisplatin-Based Doublet Therapy in Non-Small Cell Lung Cancer (NSCLC) through a Multiscale Mechanistic Model.

The 5-year survival of non-small cell lung cancer patients can be as low as 1% in advanced stages. For patients with resectable disease, the successful choice of preoperative chemotherapy is critical to eliminate micrometastasis and improve operability. In silico experimentations can suggest the opt...

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Bibliographic Details
Main Authors: Eleni Kolokotroni, Dimitra Dionysiou, Christian Veith, Yoo-Jin Kim, Jörg Sabczynski, Astrid Franz, Aleksandar Grgic, Jan Palm, Rainer M Bohle, Georgios Stamatakos
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-09-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC5033576?pdf=render

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http://europepmc.org/articles/PMC5033576?pdf=render

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