The Perturbation of Pulmonary Surfactant by Bacterial Lipopolysaccharide and Its Reversal by Polymyxin B: Function and Structure

The Perturbation of Pulmonary Surfactant by Bacterial Lipopolysaccharide and Its Reversal by Polymyxin B: Function and Structure

After inhalation, lipopolysaccharide (LPS) molecules interfere with a pulmonary surfactant, a unique mixture of phospholipids (PLs) and specific proteins that decreases surface tension at the air–liquid interphase. We evaluated the behaviour of a clinically used modified porcine pulmonary...

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Bibliographic Details
Main Authors: Maros Kolomaznik, Gilda Liskayova, Nina Kanjakova, Lukas Hubcik, Daniela Uhrikova, Andrea Calkovska
Format: Article
Language:English
Published: MDPI AG 2018-07-01
Series:International Journal of Molecular Sciences
Subjects:
pulmonary surfactant
surface activity
inhibition
lipopolysaccharide
polymyxin B
SAXS
Online Access:http://www.mdpi.com/1422-0067/19/7/1964

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http://www.mdpi.com/1422-0067/19/7/1964

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