Association of endothelin-1 and cell surface adhesion molecules levels in patients with systemic sclerosis

Endothelin-1 (ET-1) has been implicated in the pathogenesis of inflammatory and fibrotic diseases, including systemic sclerosis. In addition to modulating vascular tone and extracellular matrix turnover, ET-1 up-regulates cell surface adhesion molecules–intercellular adhesion molecule-1 (ICAM-1) and...

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Bibliographic Details
Main Authors: Mauliūtė Monika, Rugienė Rita, Žėkas Vytautas, Bagdonaitė Loreta
Format: Article
Language:English
Published: De Gruyter 2020-12-01
Series:Journal of Laboratory Medicine
Subjects:
Online Access:https://doi.org/10.1515/labmed-2020-0050