Modeling temperature- and Cav3 subtype-dependent alterations in T-type calcium channel mediated burst firing
Abstract T-type calcium channels are important regulators of neuronal excitability. The mammalian brain expresses three T-type channel isoforms (Cav3.1, Cav3.2 and Cav3.3) with distinct biophysical properties that are critically regulated by temperature. Here, we test the effects of how temperature...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2021-07-01
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Series: | Molecular Brain |
Subjects: | |
Online Access: | https://doi.org/10.1186/s13041-021-00813-7 |