Methylation in HT22 cells and primary hippocampal neurons with and without isoflurane exposurewhether isoflurane causes

Methylation in HT22 cells and primary hippocampal neurons with and without isoflurane exposurewhether isoflurane causes

Abstract Background Epigenetic modulation may play a role in anesthesia related phenotypes, such as cognitive impairment or memory loss, especially with exposure to anesthetics in the vulnerable phase of brain development. While isoflurane anesthesia can evoke neuroinflammation and neuroapoptosis in...

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Bibliographic Details
Main Authors: Stefanie Klenke, Christian Specking, Maike Stegen, Andrea Engler, Jürgen Peters
Format: Article
Language:English
Published: BMC 2020-03-01
Series:BMC Anesthesiology
Subjects:
Anesthetics
Volatile; Isoflurane
Cxcl12
Inflammation
Epigenetic changes
Gene expression
Online Access:http://link.springer.com/article/10.1186/s12871-020-00981-4

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http://link.springer.com/article/10.1186/s12871-020-00981-4

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