Active Tuberculosis Is Characterized by Highly Differentiated Effector Memory Th1 Cells

Active Tuberculosis Is Characterized by Highly Differentiated Effector Memory Th1 Cells

Despite advances in diagnosing latent Mycobacterium tuberculosis infection (LTBI), we still lack a diagnostic test that differentiates LTBI from active tuberculosis (TB) or predicts the risk of progression to active disease. One reason for the absence of such a test may be the failure of current ass...

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Bibliographic Details
Main Authors: Riccardo Arrigucci, Karim Lakehal, Pooja Vir, Deborah Handler, Amy L. Davidow, Rosa Herrera, Julia Dolores Estrada-Guzmán, Yuri Bushkin, Sanjay Tyagi, Alfred A. Lardizabal, Maria Laura Gennaro
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-09-01
Series:Frontiers in Immunology
Subjects:
FISH-Flow
T cell activation
cytokine
immunophenotyping
single-cell gene expression
memory T cells
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2018.02127/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2018.02127/full

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