Reduced estradiol-induced vasodilation and poly-(ADP-ribose) polymerase (PARP) activity in the aortas of rats with experimental polycystic ovary syndrome (PCOS).

Reduced estradiol-induced vasodilation and poly-(ADP-ribose) polymerase (PARP) activity in the aortas of rats with experimental polycystic ovary syndrome (PCOS).

Polycystic ovary syndrome (PCOS) is a complex endocrine disorder characterized by hyperandrogenism and insulin resistance, both of which have been connected to atherosclerosis. Indeed, an increased risk of clinical manifestations of arterial vascular diseases has been described in PCOS. On the other...

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Bibliographic Details
Main Authors: Gabriella Masszi, Eszter Maria Horvath, Robert Tarszabo, Rita Benko, Agnes Novak, Anna Buday, Anna-Maria Tokes, Gyorgy L Nadasy, Peter Hamar, Zoltán Benyó, Szabolcs Varbiro
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3608629?pdf=render

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http://europepmc.org/articles/PMC3608629?pdf=render

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