Blood Brain-Derived Neurotrophic Factor (BDNF) and Major Depression: Do We Have a Translational Perspective?

Major depressive disorder (MDD) affects millions of people worldwide and is a leading cause of disability. Several theories have been proposed to explain its pathological mechanisms, and the “neurotrophin hypothesis of depression” involves one of the most relevant pathways. Brain-derived neurotrophi...

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Bibliographic Details
Main Authors: Beatrice Arosio, Franca Rosa Guerini, Richard C. Oude Voshaar, Ivan Aprahamian
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-02-01
Series:Frontiers in Behavioral Neuroscience
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fnbeh.2021.626906/full