Localization of BDNF mRNA with the Huntington's disease protein in rat brain

<p>Abstract</p> <p>Background</p> <p>Studies have implicated reduced levels of brain-derived neurotrophic factor (BDNF) in the pathogenesis of Huntington's disease. Mutant huntingtin (Htt) protein was previously reported to decrease BDNF gene transcription and axon...

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Bibliographic Details
Main Authors: Chao Moses V, Tongiorgi Enrico, Baj Gabriele, Culver Brady P, Ma Bin, Tanese Naoko
Format: Article
Language:English
Published: BMC 2010-05-01
Series:Molecular Neurodegeneration
Online Access:http://www.molecularneurodegeneration.com/content/5/1/22