Medullary Thyroid Carcinoma With Exon 2 p.L56M RET Variant: Clinical Particular Features in Two Patients

Medullary Thyroid Carcinoma With Exon 2 p.L56M RET Variant: Clinical Particular Features in Two Patients

RET (REarranged during Transfection) proto-oncogene variants are essential for the development of familial and sporadic forms of medullary thyroid carcinoma (MTC). The most frequent variants are usually located in exons 10, 11, and 13 through 16 of the RET gene. We report two cases of apparently spo...

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Bibliographic Details
Main Authors: Rosa M. Paragliola, Rosa M. Lovicu, Giampaolo Papi, Ettore Capoluongo, Angelo Minucci, Giulia Canu, Alfredo Pontecorvi, Salvatore M. Corsello
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-07-01
Series:Frontiers in Endocrinology
Subjects:
medullary thyroid carcinoma
MEN2
RET
pheochromocytoma
L56M
Online Access:https://www.frontiersin.org/article/10.3389/fendo.2018.00398/full

Internet

https://www.frontiersin.org/article/10.3389/fendo.2018.00398/full

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