Decrease of the DNA methylation levels of the ADRB3 gene in leukocytes is related with serum folate in eutrophic adults

Decrease of the DNA methylation levels of the ADRB3 gene in leukocytes is related with serum folate in eutrophic adults

Abstract Background DNA methylation has been evidenced as a potential epigenetic mechanism related to various candidate genes to development of obesity. Therefore, the objective of this study was to evaluate the DNA methylation levels of the ADRB3 gene by body mass index (BMI) in a representative ad...

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Main Authors: Yohanna de Oliveira, Raquel Patrícia Ataíde Lima, Rafaella Cristhine Pordeus Luna, Mussara Gomes Cavalcanti Alves Monteiro, Cássia Surama Oliveira da Silva, Rayner Anderson Ferreira do Nascimento, Keylha Querino de Farias Lima, Ana Hermínia Andrade e Silva, Flávia Emília Leite de Lima Ferreira, Rodrigo Pinheiro de Toledo Vianna, Ronei Marcos de Moraes, Naila Francis Paulo de Oliveira, Aléssio Tony Cavalcanti de Almeida, Alexandre Sérgio Silva, Alcides da Silva Diniz, Maria José de Carvalho Costa, Maria da Conceição Rodrigues Gonçalves
Format: Article
Language:English
Published: BMC 2018-06-01
Series:Journal of Translational Medicine
Subjects:
ADRB3
DNA methylation
Body mass index
Folic acid
Online Access:http://link.springer.com/article/10.1186/s12967-018-1529-0

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http://link.springer.com/article/10.1186/s12967-018-1529-0

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