Phenotypic changes in the brain of SIV-infected macaques exposed to methamphetamine parallel macrophage activation patterns induced by the common gamma-chain cytokine system

One factor in the development of neuroAIDS is the increase in the migration of pro-inflammatory CD8 T cells across the Blood Brain Barrier. Typically these cells are involved with keeping the viral load down. However, the persistence of above average numbers of CD8 T cells in the brain, not necessar...

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Bibliographic Details
Main Authors: Nikki eBortell, Brenda eMorsey, Liana eBasova, Howard S Fox, Maria Cecilia G Marcondes
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-09-01
Series:Frontiers in Microbiology
Subjects:
SIV
Online Access:http://journal.frontiersin.org/Journal/10.3389/fmicb.2015.00900/full