Optimization of multivariate regression methods for quantification of sulphamethoxazole and trimethoprim in pharmaceutical formulations

Optimization of multivariate regression methods for quantification of sulphamethoxazole and trimethoprim in pharmaceutical formulations

A partial least-squares calibration (PLS) procedure in combination with infrared spectroscopy has been developed for simultaneous determination of sulphamethoxazole (SMZ) and trimethoprim (TMP) in powder raw material mixtures used for manufacturing commercial pharmaceutical products. Multivariate ca...

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Bibliographic Details
Main Authors: Fabiana Ernestina Barcellos da Silva, Gustavo Post Sabin, Edson Irineu Müller, Graciele Parisotto, Érico Marlon de Moraes Flores, Marco Flores Ferrão
Format: Article
Language:English
Published: Universidade Federal de Santa Catarina 2008-07-01
Series:Revista Produção Online
Online Access:http://producaoonline.org.br/rpo/article/view/50

Internet

http://producaoonline.org.br/rpo/article/view/50

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