FGF2/FGFR1 regulates autophagy in FGFR1-amplified non-small cell lung cancer cells

Abstract Background Autophagy is a conserved catabolic process to degrade cellular organelles. The role of autophagy in cancer development is complex. Amplification of fibroblast growth factor receptor 1 (FGFR1) is one of the most frequent targets in lung squamous cell carcinoma (SQCC). Whether fibr...

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Bibliographic Details
Main Authors: Hong Yuan, Zi-Ming Li, Jiaxiang Shao, Wen-Xiang Ji, Weiliang Xia, Shun Lu
Format: Article
Language:English
Published: BMC 2017-05-01
Series:Journal of Experimental & Clinical Cancer Research
Subjects:
ERK
Online Access:http://link.springer.com/article/10.1186/s13046-017-0534-0