Acetylcholinesterase inhibitors with a thiazolium scaffold: structural features and binding modes
Aim. To assess the structural features of substituents and the role of a thiazolium scaffold in mechanisms of acetylcholinesterase inhibition by thiazolium salts. Results and discussion. On the basis of activities of model compounds at pH 6.5 and pH 8.0 and the results of molecular docking the bind...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
National University of Pharmacy (Kharkiv, Ukraine)
2019-05-01
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| Series: | Журнал органічної та фармацевтичної хімії |
| Subjects: | |
| Online Access: | http://ophcj.nuph.edu.ua/article/view/ophcj.19.971/170518 |