Chimeric Antigen Receptor T-Cell Therapy Clinical Results in Pediatric and Young Adult B-ALL

Abstract. Chimeric antigen receptor (CAR)-modified T-cell therapy has revolutionized the care of patients with relapsed and refractory B-cell acute lymphoblastic leukemia (B-ALL). Results from clinical trials across multiple institutions report remarkable remission rates with CD19-directed CAR-modif...

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Bibliographic Details
Main Authors: Amanda M. DiNofia, Shannon L. Maude
Format: Article
Language:English
Published: Wolters Kluwer 2019-08-01
Series:HemaSphere
Online Access:http://journals.lww.com/10.1097/HS9.0000000000000279