Cell fate in antiviral response arises in the crosstalk of IRF, NF-κB and JAK/STAT pathways

Cell fate in antiviral response arises in the crosstalk of IRF, NF-κB and JAK/STAT pathways

Innate immunity combines intra- and intercellular signalling to develop responses that limit pathogen spread. Here the authors analyse feedback and feedforward loops connecting IRF3, NF-κB and STAT pathways, and suggest they allow coordinating cell fate decisions in cellular populations in response...

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Bibliographic Details
Main Authors: Maciej Czerkies, Zbigniew Korwek, Wiktor Prus, Marek Kochańczyk, Joanna Jaruszewicz-Błońska, Karolina Tudelska, Sławomir Błoński, Marek Kimmel, Allan R. Brasier, Tomasz Lipniacki
Format: Article
Language:English
Published: Nature Publishing Group 2018-02-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-017-02640-8

Internet

https://doi.org/10.1038/s41467-017-02640-8

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