Characterizing the Binding Sites for GK Domain of DLG1 and DLG4 via Molecular Dynamics Simulation

Discs-large (DLG) is a member that belongs to the membrane-associated guanylate kinase (MAGUK) family. The GK domain of DLGs has evolved into a protein–protein interaction module that could bind with kinds of proteins to regulate diverse cellular functions. Previous reports have demonstrated the GK...

Full description

Bibliographic Details
Main Authors: Hongwei Li, Qiong Chen, Changyu Shan, Chunling Guo, Xiuming Yang, Yingchun Chen, Jinwei Zhu, Qin Ouyang
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-01-01
Series:Frontiers in Molecular Biosciences
Subjects:
DLG
Online Access:https://www.frontiersin.org/article/10.3389/fmolb.2020.00001/full