Stable Epigenetic Programming of Effector and Central Memory CD4 T Cells Occurs Within 7 Days of Antigen Exposure In Vivo

Stable Epigenetic Programming of Effector and Central Memory CD4 T Cells Occurs Within 7 Days of Antigen Exposure In Vivo

T cell immunological memory is established within days of an infection, but little is known about the in vivo changes in gene regulatory networks accounting for their ability to respond more efficiently to secondary infections. To decipher the timing and nature of immunological memory we performed g...

Full description

Bibliographic Details
Main Authors: Sarah L. Bevington, Remi Fiancette, Dominika W. Gajdasik, Peter Keane, Jake K. Soley, Claire M. Willis, Daniel J. L. Coleman, David R. Withers, Peter N. Cockerill
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-05-01
Series:Frontiers in Immunology
Subjects:
memory T CD4+ cells
gene regulatory networks
epigenetics (chromatin remodelling)
immunological memory responses
T cell activation
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.642807/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2021.642807/full

Similar Items