A distance based multisample test for high-dimensional compositional data with applications to the human microbiome

Abstract Background Compositional data refer to the data that lie on a simplex, which are common in many scientific domains such as genomics, geology and economics. As the components in a composition must sum to one, traditional tests based on unconstrained data become inappropriate, and new statist...

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Bibliographic Details
Main Authors: Qingyang Zhang, Thy Dao
Format: Article
Language:English
Published: BMC 2020-12-01
Series:BMC Bioinformatics
Subjects:
Online Access:https://doi.org/10.1186/s12859-020-3530-x