IL-27-induced gene expression is downregulated in HIV-infected subjects.

OBJECTIVE: To characterize the effect of HIV infection on IL-27-induced gene expression. DESIGN: During HIV infection, cytokine expression and function become deregulated. IL-27 is an important modulator of inflammatory responses. Interestingly, IL-27 can inhibit HIV replication in T cells and monoc...

Full description

Bibliographic Details
Main Authors: Christina Guzzo, Wilma M Hopman, Nor Fazila Che Mat, Wendy Wobeser, Katrina Gee
Format: Article
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access: