Genome wide SNP comparative analysis between EGFR and KRAS mutated NSCLC and characterization of two models of oncogenic cooperation in non-small cell lung carcinoma

<p>Abstract</p> <p>Background</p> <p>Lung cancer with EGFR mutation was shown to be a specific clinical entity. In order to better understand the biology behind this disease we used a genome wide characterization of loss of heterozygosity and amplification by Single Nuc...

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Bibliographic Details
Main Authors: Tremblay-Gravel Maxime, Danel Claire, Le Corre Delphine, Pallier Karine, Blons Hélène, Houdayer Claude, Fabre-Guillevin Elizabeth, Riquet Marc, Dessen Philippe, Laurent-Puig Pierre
Format: Article
Language:English
Published: BMC 2008-06-01
Series:BMC Medical Genomics
Online Access:http://www.biomedcentral.com/1755-8794/1/25