p63α and γ Induce TAU Phosphorylation in Cultured Mammalian Cells
Here we show by western blotting that transcriptionally active isoforms of p63 (p63α and p63γ) induce the phosphorylation of human 2N4R tau at the tau-1/AT8 epitope in HEK293a cells; a phospho-epitope increased in Alzheimer's disease. Confocal microscopy shows that tau and p63α are spatially se...
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
SAGE Publishing
2010-01-01
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| Series: | Journal of Experimental Neuroscience |
| Online Access: | https://doi.org/10.4137/JEN.S6295 |